Regenerative aesthetic biostimulation
Injectable platelet rich fibrin or (iPRF) is a unique rejuvenation technique that uses the patient’s own blood plasma, enriched with platelets (source of healing proteins and growth factors), fibrin (the wound healing and regeneration matrix) and stem cells (the conductors of our body’s own healing and regenerative orchestra of healing and regeneration molecules).
The resulting product is then injected into areas with desired end results to activate accelerated healing and regeneration. As a result, the body’s own powerful regenerative properties are concentrated and focused on the area of concern to trigger innate biological mechanisms which lead to natural skin rejuvenation.
iPRF intensifies the functioning and reproduction of cells, thus having a gentle, gradual yet long lasting and accumulative effect. As a result new fibroblasts, collagen and elastin tissues are formed, skin elasticity and complexion is improved, and the pigmentation is reduced.
Our clinic has been working closely with Dr Joseph Choukroun; the inventor of iPRF technology, to unlock the development of this technology further into clients’ focused clinical indications.
Is this the same as PRP? What is the difference between iPRF & PRP?
Both PRP (platelet rich plasma), and PRF (platelet rich fibrin) are platelet based growth factor treatments that are extracted using centrifuge. PRF is different from PRP in that there is no anticoagulant added during the spin, the avoidance of clotting is physiological and is achieved through negative charge of the collecting tube to mimic the conditions within our own blood vessels (their lining is negatively charged) that prevent fibrin from creating a clot within them, thus, obtaining a platelet rich injectable fibrin. Once PRF is injected in the tissue it transforms from liquid into a gel, which not only lead to filling of voids in folds and wrinkles but also provide a powerful regenerative matrix that releases platelets’ growth factors in a physiological controlled slow manner that enhances tissue regeneration is a better way than PRP.
In addition, the enrichment of platelets in these two products is not the same. In PRP, the platelets are enriched two to four times above the physiological concentrations available in blood and there are very few circulating blood stem cells. In contrast, PRF contains all the platelets with no elimination of the powerful regenerative matrix (fibrin) in addition to another very rich source of growth factors and tissue regeneration: the circulating blood regenerative cells.
Why fibrin is important?
Dr Choukroun explains that Fibrin functions as a matrix that traps the platelets and controls their release of growth factors “very slowly and continuously over a time period of more than one week”. Growth factors release rate into the target tissue is important for tissue receptors to respond over a prolonged period of time following treatment. “It’s not the amount of growth factors that’s the most important, but it is released into the site. To treat severe infection, antibiotics can be injected drop by drop in an IV perfusion, ensuring that a stable concentration is maintained. This is the same in PRF biology—to obtain the most important function a stable concentration must be maintained. The best is a drop-by-drop infusion”
Aesthetic Regenerative Use of PRF
Platelet growth factors in a fibrin scaffold is the first response to injury observed in all human tissue. Thus, the applications of PRF for healing and regeneration are not limited only to skin. Accelerated healing, new blood vessels and proliferation of cells producing collagen (fibroblasts) have been well demonstrated in biomedical research investigating the basic functions of regenerative products. Our doctors will discuss with you at your consultation how PRF could be used alone or in combination with other treatment to address your aesthetic regenerative concerns from skin rejuvenation to tissue regeneration.
iPRF Hair Growth Treatment
This is an all-natural non-surgical therapeutic option for patients who suffer from hair loss or thinning. iPRF can enhance the growth of hair follicles by stimulating the regenerative cells and other cells in the microenvironment of the hair follicle. These special Platelet cells promote healing and accelerates the rate and degree of tissue regeneration, resulting in new hair growth and thickening of existing hair.
We are pleased to offer our clients to affordable and frexible finance options to enable you to receive holistic comprehensive aesthetic regenerative treatments. Learn more